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Roberttig | Дата: Вторник, 01.07.2014, 22:26 | Сообщение # 258 |
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Monitor patients intimately Uses: *Rx Hep C* Action: Immune modulation Dose: 1 mcg/kg/wk SQ; 1.5 mcg/kg/wk occluded w/ribavirin Caution: <C> ?/Ц - w/psychiatric Hx Contra: Autoimmune hepatitis, decompensated liver Dz, haemoglobinopathy Disp: Vials 50, 80, 120, cardinal mcg/0.5 mL; Redipen 50, 80,120,150 mcg/5 mL; structure w/0.7 mL w/sterile piddle SE: Depression, insomnia, suicidal behavior, GI upset, neutropenia, thrombocytopenia, alopecia, pruritus Notes: Give hs or w/APAP to v flu-like Sxs; varan CBC/platelets; apply immediately or accumulation in icebox . 24 h; do not suspend Pemetrexed (Alimta) Uses: *w/ cisplatin in nonresectable mesothelioma* NSCLC Action: Antifolate antitumour Dose: cardinal mg/m2 IV over 10 min every 3 wk; concord if CrCl <45 mL/min; snap w/ vitamin B12 (1000 mcg IM every 9 wk) & folic resolvent (350Ц1000 mcg PO daily); commence 1 wk before; corticosteroid 4 mg PO offering . 3 sign 1 d ahead apiece Rx Caution: <D> Ц - w/ renal/hepatic/ 166 Pemirolast BM spoil Contra: Component sensation Disp: 500-mg ampoule SE: Neutropenia, thrombocytopenia, N/V/D, anorexia, stomatitis, nephritic failure, neuropathy, fever, fatigue, mood changes, dyspnea, anaphylactic Rxns Notes: Avoid NSAIDs, trace CBC/platelets Pemirolast (Alamast) Uses: *Allergic conjunctivitis* Action: Mast cadre stabilizer Dose: 1Ц2 gtt in apiece discernment qid Caution: <C> ?/Ц - Disp: 0.1% (1 mg/ml) in 10-mL bottles SE: HA, rhinitis, cold/flu symptoms, anaesthetic aggression Notes: Wait 10 min earlier inserting contacts Penbutolol (Levatol) Uses: *HTN* Action: .-adrenergic organ blocker, .1, .2 Dose: 20Ц40 mg/d; v in liverwort insuff Caution: <C>ordinal tri; D if 2nd/3rd tri, M - Contra: Asthma, cardiogenic shock, cardiac failure, disposition block, bradycardia, COPD, pulm lump Disp: Tabs 20 mg SE: Flushing, v BP, fatigue, hyperglycemia, GI upset, sexy dysfunction, bronchospasm Penciclovir (Denavir) Uses: *Herpes simplex (herpes labialis/cold sores)* Action: Competitive inhibitor of polymer polymerase Dose: Apply at ordinal signal of lesions, then q2h patch alert . 4 d Caution: <B> ?/Ц - Contra: Allergy, preceding Rxn to famiciclovir Disp: Cream 1% <OTC>- SE: Erythema, HA Notes: Do not apply to secretion membranes Penicillin G, Aqueous (Potassium or Sodium) (Pfizerpen, Pentids) Uses: *Bacteremia, endocarditis, pericarditis, resp pathway Infxns, meningitis, neurosyphilis, skin/skin toy Infxns* Action: Bactericidal; v radiotelephone wall synth. Peds. 3Ц6 mg/kg/d in 3 . doses; v w/renal impair, Caution: <C> + - display w/hepatic impair, ^ conc with amiodarone, digoxin, quinidine, ritonavir/amprenavir, BB, verapamil; may exasperate arrhythmias Contra: 2nd-/3rd-degree AV block, RBBB w/ bifascicular or trifascicular block, cardiogenic shock, CAD, ritonavir/amprenavir, alkalinizing agents Disp: Tabs 50, 100, cardinal mg SE: Dizziness, optical disturbances, dyspnea, palpitations, edema, breast pain, tachycardia, CHF, HA, fatigue, rash, N Notes: Initiate Rx in hospital; pane q8h if pt is intolerant/uncontrolled at q12h; Levels: Trough: virtuous earlier incoming dose: Therapeutic: 0.2Ц1 mcg/mL; Toxic >1 mcg/mL; 1.2 life: 11Ц14 h Floxuridine (FUDR) WARNING: Administration by intimate medico only; patients should be hospitalized for archetypical path owed to danger for life-threatening rxn Uses: *GI adenoma, liver, nephritic cancers*; punctuation & pancreatic CAs Action: Converted to 5 FU; inhibits thymidylate synthase; v polymer synth (S-phase specific) Dose: 0.1Ц0.6 mg/kg/d for 1Ц6 wk (per protocols) unremarkably intra arterial for liver-colored mets Caution: <D> Ц - Interaction w/ vaccines Contra: BM suppression, deficient nutritionary status, potentially solemn Infxn Disp: Inj cardinal mg SE: v BM, anorexia, abd cramps, N/V/D, mucositis, alopecia, cutis rash, & hyperpigmentation; extraordinary neurotox (blurred vision, depression, nystagmus, vertigo, & lethargy); intra-arterial catheterrelated problems (ischemia, thrombosis, bleeding, & Infxn) Notes: Need efficacious birth control; cure Rx for inoperable/incurable pts Fluconazole (Diflucan) Uses: *Candidiasis (esophageal, oropharyngeal, urinary tract, vaginal, prophylaxis); cryptococcal meningitis* Action: Antifungal; v cytochrome P-450 alcohol demethylation. 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